Geodetic Monitoring of the Retaining Wall SO233 on the Frýdek-Místek Bypass

Předložená diplomová práce se zabývá geodetickým monitoringem za účelem zjištění pohybů a deformací staveb, vzniku těchto jevů, a hlavně jejich zaměřením a vyhodnocením. V první části práce jsou teoreticky popsány úskalí měření pohybů a deformací. V druhé části se jedná o aplikaci a využití na konkrétním stavebním objektu. Pro měření svislých pohybů byla zvolena metoda přesné nivelace. Byl použit nivelační přístroj Leica LS10 0,3 mm v kombinací s invarovou kódovanou latí o délce 3 m. Největší naměřený pokles se vyskytuje přibližně uprostřed zdi, kde byl naměřen celkový pokles 12 mm. Sledování vodorovných pohybů bylo realizováno polární metodou z přechodného stanoviska. Na základech rozborů přesnosti byla vhodně vybrána totální stanice Leica TS16 1". Dosažená přesnost měření byla rozborem přesnosti stanovena na ∅σ_x = ̇1,5 mm a ∅σ_y = ̇2,5 mm v jednotlivých souřadnicových osách. Po rozšíření koeficientem spolehlivosti U_P=2 byla stanovena mezní směrodatná odchylka metody na δ_x=3 mm a δ_y=5 mm. Největší zjištěný vodorovný pohyb v příčném i podélném směru dosahoval velikosti 3 mm. Naměřené hodnoty při sledování opěrné zdi nepřesahují stanovené meze, a můžeme tedy říci, že tyto naměřené pohyby a deformace nemají vliv na stabilitu, funkci nebo bezpečnost opěrné zdi SO 233.The submitted master thesis deals with geodetic monitoring in order to determine the movements and deformations of buildings, the occurrence of these phenomena, and especially their focus and evaluation. The first part of the thesis theoretically describes the pitfalls of measuring movements and deformations. The second part deals with the application and use on a specific building. The method of precise leveling was chosen to measure vertical movements. A Leica LS10 0.3 mm leveling instrument was used in combination with an invar coded bar with a length of 3 m. The largest measured drop occurs approximately in the middle of the wall, where a total drop of 12 mm was measured. Monitoring of horizontal movements was performed by the polar method from a transient standpoint. The Leica TS16 1" total station was appropriately selected on the basis of accuracy analyzes. The achieved measurement accuracy was determined to be ∅σ_x = ̇1,5 mm and ∅σ_y = ̇2,5 mm in the individual coordinate axes. After extension by the reliability coefficient U_P=2, the limit standard deviation of the method was set to δ_x=3 mm and δ_y=5 mm. The largest detected horizontal movement in the transverse and longitudinal direction reached a size of 3 mm. The measured values when monitoring the retaining wall do not exceed the specified limits, and we can therefore say that these measured movements and deformations do not affect the stability, function or safety of the retaining wall SO 233.544 - Katedra geodézie a důlního měřictvívýborn

Quality Management in the Company XYZ

Tato diplomová práce se zaměřuje na efektivní řízení ekonomiky kvality v mezinárodním podniku působícím v České republice, věnuje se standardnímu i modernímu pojetí řízení ekonomiky kvality a teoretické podstatě řízení nákladů souvisejících s kvalitou. Hlavním cílem této diplomové práce je definování, výběr a implementace optimálního modelu monitorování nákladů souvisejících s kvalitou, pro konkrétní společnost. V rámci implementace vybraného modelu monitorování, před započetím samotné realizace, bude zpracován projektový plán, včetně detailní analýzy rizik náležících jednotlivým fázím realizace projektu. Dalším krokem v aplikaci projektu, bude definování příslušných nákladových položek, které budou v následné fázi vyhodnoceny a optimalizovány.This master´s thesis is focused on efficient control of quality economy in an international company operating in the Czech Republic. It relates to standard and modern concept of quality economy management and theoretical basis of cost management related to quality. The purpose of this thesis is to define, choose and implement the best model of monitoring quality related costs. As a part of the implementation phase of the chosen model, project plan including risk analyses which belongs to individual project's phases will be created, cost related actions defined and in the next phase evaluated and optimized.

Handling of Meat and Bone Meal

Import 04/07/2011Bakalářská práce je věnována problematice nakládání s masokostní moučkou. V práci je popsána historie nakládání s vedlejšími živočišnými materiály, technologie výroby masokostní moučky a její využití. Zabývá se problémem, proč je masokostní moučka nebezpečný odpad. Masokostní moučka je známa už od počátku 20. století. Vyrábí se ve veterinárních asanačních ústavech z vedlejších živočišných produktů. Současné využití masokostní moučky je mnohostranné. V zemědělství se používá ke krmení, hnojení a kompostování. Je surovinou pro bioplynové stanice, palivem při spalování v cementářských pecích.The bachelor thesis is devoted to the problems of handling meat and bone meal. The thesis describes the history of waste animal by-product handling, production technology of meat and bone meal and its use. It deals with the problems why meat and bone meal is hazardous waste. Meat and bone meal has been known since the beginning of the 20th century. It is produced from animal by-products in veterinary rehabilitation institutes. Current use of meat and bone meal is versatile. In agriculture it is used for feed, fertilization and composting. It is a raw material for biogas stations and/or fuel cement furnaces.Prezenční546 - Institut environmentálního inženýrstvívýborn

Design of an internet of things based real-time monitoring system for retired patients

The main aim of this article is to design a monitoring center for collecting and evaluating the physiological function of retired patients in nursing homes. The system should be able to collect the information of body heat, heart rate, blood oxygen, orientation, and sleep time in the form of the little bracelet. The evaluating part of the system with the program can be placed into personal computer (PC) which can provide a user-friendly interface and easy managing. The program can display all needed information of the patient from previous days or months in the form of the graphs and the nursing person can have the view of the patient´s physiological health. The evaluation and the collection of the data from each patient are done only on the card and the computer is only a device for live-view and managing. In case of the power failure, the monitoring system will be still operating normally due to the uninterruptible power supply (UPS) in the form of the battery. It means that the system will operate even if the PC is powered off. The system also has several external communication interfaces like wireless fidelity (Wi-Fi), ethernet, and general packet radio service (GPRS) which provides an external connection. © 2021, Institute of Advanced Engineering and Science. All rights reserved.IGA/CebiaTech/2020/003; Ministerstvo Školství, Mládeže a Tělovýchovy, MŠMT: LO1303, MSMT-7778/2014; European Regional Development Fund, ERDF: CEBIA-Tech ED2.1.00/03.008

Blanket Restrictive Measures in the Czech Republic During the COVID-19 Pandemic – A Trade-Off Concept Application

In early 2020, many widespread restrictive measures were introduced worldwide in response to the COVID-19 pandemic. These measures entailed high socio-economic costs, which have been largely overlooked due to political motivations and the difficulty of their measurement. One of them is the negative impact of widespread restrictive measures on life expectancy due to the limited school attendance and the negative impact of restrictions on the population's health status. In this paper, we use our own structural model based on the trade-off analysis method. The research compares the lost years of life in the situation of the existence of restrictive measures and, on the contrary, the situation of a complete absence of these measures. We use data from the Czech Republic between February 2020 and October 2021. Our article concludes that the number of lost years of life is many times higher when widespread restrictive measures are implemented in all considered scenarios. These findings should be considered when making further decisions on applying widespread restrictive measures in the Czech Republic

EFFECT OF ECOLOGICAL ENERGY CARRIERS ON FLOW CHARACTERISTICS OF TRACTOR HYDRAULIC PUMP

This paper deals with the effect of ecological energy carrier on flow characteristics of a hydraulic pump. A hydraulic oil MOL Farm UTTO Synt was used as an ecological energy carrier. After completing 900 engine hours, the flow efficiency of the hydraulic pump decreased by Δηpr = 1.197 %. Oil samples were taken from the agricultural tractor Zetor Forterra 114 41. These samples were subjected to an IR spectroscopy analysis in an accredited laboratory WearCheck, Hungary. The following oil properties were examined: kinematic viscosity at 40 °C, viscosity index, silicium and ferrum content

ZnO/Cu2O heterojunctions treated glass surface for photocatalytic and self-cleaning applications

Here we report the synthesis route for glass surface functionalization by ZnO nanorods and nanowires-based Cu2O heterojunction. In the first step, ZnO elongated structures were grown on a seeded substrate following the classic hydrothermal method, and their thickness can be controlled by polyethyleneimine (PEI) concentration. In the second step, ZnO/Cu2O heterojunctions were fabricated by immersion of ZnO-grown substrate upside-down into the copper sulfate solution with glucose as a reducing agent. After characterization of prepared ZnO/Cu2O heterojunction by SEM, TEM, and XRD, its application capability for waste-water treatment was successfully demonstrated on Estriol (E3) hormone degradation under UV light by using a continuous Drip Flow Biofilm Reactor. Furthermore, functionalized glasses were shown to be effective for designing self-cleaning surfaces. The photocatalytic-induced self-cleaning ability was demonstrated by resazurin-based smart ink and tert-butyl alcohol-based methylene blue ink. © 2023 TANGER Ltd., Ostrava.Ministerstvo Školství, Mládeže a Tělovýchovy, MŠMT: LTT20010, RP/CPS/2022/00

XXV. mezinárodní kolokvium o regionálních vědách

Title in English: 25th International Colloquium on Regional Sciences: Conference proceedings The conference proceedings consists of papers presented at the 25th International Colloquium on Regional Sciences that was organized by Department of Regional Economics and Administration FEA MU. It contains 57 articles arranged by topic. The individual articles deal with e.g. socioeconomic disparities among regions, regional policy, territory attractiveness, tourism, or regional public administration

EPMA-World Congress 2015: Bonn, Germany. 3-5 September 2015

Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of IDO in a murine model of gingivitis: predictive and therapeutic potentials Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari A6 Specific diets for personalised treatment of diabetes type 2 Viktoriia V. Bati, Tamara V. Meleshko, Olga B. Levchuk, Nadiya V. Boyko A7 Towards personalized physiotherapeutic approach Joanna Bauer, Ewa Boerner, Halina Podbielska A8 Cells, animal, SHIME and in silico models for detection and verification of specific biomarkers of non-communicable chronic diseases Alojz Bomba, Viktor O. Petrov, Volodymyr G. Drobnych, Rostyslav V. Bubnov, Oksana M. Bykova, Nadiya V. Boyko A9 INTERACT-chronic care model: Self-treatment by patients with decision support e-Health solution Hans-Peter Brunner-La Rocca, Lutz Fleischhacker, Olga Golubnitschaja, Frank Heemskerk, Thomas Helms, Tiny Jaarsma, Judita Kinkorova, Jan Ramaekers, Peter Ruff, Ivana Schnur, Emilio Vanoli, Jose Verdu A10 PPPM in cardiovascular medicine in 2015 Hans-Peter Brunner-La Rocca A11 Magnetic resonance imaging of nanoparticles in mice, potential for theranostic and contrast media development – pilot results Rostyslav V. Bubnov, Sergiy A. Grabovetskyi, Olena M. Mykhalchenko, Natalia O. Tymoshok, Oleksandr B. Shcherbakov, Igor P. Semeniv, Mykola Y. Spivak A12 Ultrasound diagnosis for diabetic neuropathy - comparative study Rostyslav V. Bubnov, Tetyana V. Ostapenko A13 Ultrasound for stratification patients with diabetic foot ulcers for prevention and personalized treatment - pilot results Rostyslav V. Bubnov, Nazarii M. Kobyliak, Nadiya M. Zholobak, Mykola Ya. Spivak A14 Project ImaGenX – designing and executing a questionnaire on environment and lifestyle risk of breast cancer John Paul Cauchi A15 Genomics – a new structural brand of predictive, preventive and personalized medicine or the new driver as well? Dmitrii Cherepakhin, Marina Bakay, Artem Borovikov, Sergey Suchkov A16 Survey of questionnaires for evaluation of the quality of life in various medical fields Barbara Cieślik, Agnieszka Migasiewicz, Maria-Luiza Podbielska, Markus Pelleter, Agnieszka Giemza, Halina Podbielska A17 Personalized molecular treatment for muscular dystrophies Sebahattin Cirak A18 Secondary mutations in circulating tumour DNA for acquired drug resistance in patients with advanced ALK + NSCLC Marzia Del Re, Paola Bordi, Valentina Citi, Marta Palombi, Carmine Pinto, Marcello Tiseo, Romano Danesi A19 Recombinant species-specific FcεRI alpha proteins for diagnosis of IgE-mediated allergies in dogs, cats and horses Lukas Einhorn, Judit Fazekas, Martina Muhr, Alexandra Schoos, Lucia Panakova, Ina Herrmann, Krisztina Manzano-Szalai, Kumiko Oida, Edda Fiebiger, Josef Singer, Erika Jensen-Jarolim A20 Global methodology for developmental neurotoxicity testing in humans and animals early and chronically exposed to chemical contaminants Arpiné A. Elnar, Nadia Ouamara, Nadiya Boyko, Xavier Coumoul, Jean-Philippe Antignac, Bruno Le Bizec, Gauthier Eppe, Jenny Renaut, Torsten Bonn, Cédric Guignard, Margherita Ferrante, Maria Liusa Chiusano, Salvatore Cuzzocrea, Gerard O'Keeffe, John Cryan, Michelle Bisson, Amina Barakat, Ihsane Hmamouchi, Nasser Zawia, Anumantha Kanthasamy, Glen E. Kisby, Rui Alves, Oscar Villacañas Pérez, Kim Burgard, Peter Spencer, Norbert Bomba, Martin Haranta, Nina Zaitseva, Irina May, Stéphanie Grojean, Mathilde Body-Malapel, Florencia Harari, Raul Harari, Kristina Yeghiazaryan, Olga Golubnitschaja, Vittorio Calabrese, Christophe Nemos, Rachid Soulimani A21 Mental indicators at young people with attributes hypertension and pre-hypertension Maria E. Evsevyeva, Elena A. Mishenko, Zurida V. Kumukova, Evgeniy V. Chudnovsky, Tatyana A. Smirnova A22 On the approaches to the early diagnosis of stress-induced hypertension in young employees of State law enforcement agencies Maria E. Evsevyeva, Ludmila V. Ivanova, Michail V. Eremin, Maria V. Rostovtseva A23 Сentral aortic pressure and indexes of augmentation in young persons in view of risk factors Maria E. Evsevyeva, Michail V. Eremin, Vladimir I. Koshel, Oksana V. Sergeeva, Nadesgda M. Konovalova A24 Breast cancer prediction and prevention: Are reliable biomarkers in horizon? Shantanu Girotra, Olga Golubnitschaja A25 Flammer Syndrome and potential formation of pre-metastatic niches: A multi-centred study on phenotyping, patient stratification, prediction and potential prevention of aggressive breast cancer and metastatic disease Olga Golubnitschaja, Manuel Debald, Walther Kuhn, Kristina Yeghiazaryan, Rostyslav V. Bubnov, Vadym M. Goncharenko, Ulyana Lushchyk, Godfrey Grech, Katarzyna Konieczka A26 Innovative tools for prenatal diagnostics and monitoring: improving individual pregnancy outcomes and health-economy in EU Olga Golubnitschaja, Jan Jaap Erwich, Vincenzo Costigliola, Kristina Yeghiazaryan, Ulrich Gembruch A27 Immunohistochemical assessment of APUD cells in endometriosis Vadym M. Goncharenko, Vasyl O. Beniuk, Olga V. Kalenska, Rostyslav V. Bubnov A28 Updating personalized management algorithm of endometrial hyperplasia in pre-menopause women Vadym M. Goncharenko, Vasyl O. Beniuk, Rostyslav V. Bubnov, Olga Melnychuk A29 The personified treatment approach of polimorbid patients with periodontal inflammatory diseases Irina A. Gorbacheva, Lyudmila Y. Orekhova, Vadim V. Tachalov A30 Ukrainian experience in hybrid war – the challenge to update algorithms for personalized care and early prevention of different military injuries Olena I. Grechanyk, Rizvan Ya. Abdullaiev, Rostyslav V. Bubnov A31 Tear fluid biomarkers: a comparison of tear fluid sampling and storage protocols Suzanne Hagan, Eilidh Martin, Ian Pearce, Katherine Oliver A32 The correlation of dietary habits with gingival problems during menstruation Cenk Haytac, Fariz Salimov, Servin Yoksul, Anatoly A. Kunin, Natalia S. Moiseeva A33 Genomic medicine in a contemporary Spanish population of prostate cancer: our experience Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara, Antonia Angulo, Francisco Javier Machuca Santa-Cruz A34 Challenges, opportunities and collaborations for personalized medicine applicability in uro-oncological disease Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara A35 Metabolic hallmarks of cancer as targets for a personalized therapy John Ionescu A36 Influence of genetic polymorphism as a predictor of the development of periodontal disease in patients with gastric ulcer and 12 duodenal ulcer Alfiya Z. Isamulaeva, Anatoly A. Kunin, Shamil Sh. Magomedov, Aida I. Isamulaeva A37 Challenges in diabetic macular edema Tatjana Josifova A38 Overview of the EPMA strategies in laboratory medicine relevant for PPPM Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja, Vincenzo Costigliola A39 EPMA initiative for effective organization of medical travel: European concepts and criteria Vincenzo Costigliola, Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja A40 Design and innovation in e-textiles: implications for PPPM Anthony Kent, Tom Fisher, Tilak Dias A41 Biobank in Pilsen as a member of national node BBMRI_CZ Judita Kinkorová, Ondřej Topolčan A42 Big data in personalized medicine: hype and hope Matthias Kohl A43 The 3P approach as the platform of the European Dentistry Department (DPPPD) Anatoly A. Kunin, Natalia S. Moiseeva A44 The endometrium cytokine patterns for predictive diagnosis of proliferation severity and cancer prevention Andrii I. Kurchenko, Vasyl A. Beniuk, Vadym M. Goncharenko, Rostyslav V. Bubnov, Nadiya V. Boyko, Andriy M. Strokan A45 A monocyte-based in-vitro system for testing individual responses to the implanted material: future for personalized implant construction Julia Kzhyshkowska, Alexandru Gudima, Ksenia S. Stankevich, Victor D. Filimonov4, Harald Klüter, Evgeniya M. Mamontova, Sergei I. Tverdokhlebov A46 Prediction and prevention of adverse health effects by meteorological factors: Biomarker patterns and creation of a device for self-monitoring and integrated care Ulyana B. Lushchyk, Viktor V. Novytskyy, Igor P. Babii, Nadiya G. Lushchyk, Lyudmyla S. Riabets, Ivanna I. Legka A47 Targeting "disease signatures" towards personalized healthcare Mira Marcus-Kalish, Alexis Mitelpunkt, Tal Galili, Neta Shachar, Yoav Benjamini A48 Influence of the skin imperfection on the personal quality of life and possible tools for objective diagnosis Agnieszka Migasiewicz, Markus Pelleter, Joanna Bauer, Ewelina Dereń, Halina Podbielska A49 The new direction in caries prevention based on the ultrastructure of dental hard tissues and filling materials Natalia S. Moiseeva, Anatoly A. Kunin, Dmitry A. Kunin A50 The use of LED radiation in prevention of dental diseases Natalia S. Moiseeva, Yury A. Ippolitov, Dmitry A. Kunin, Alexei N. Morozov, Natalia V. Chirkova, Nakhid T. Aliev A51 Status of endothelial progenitor cells in diabetic nephropathy: predictive and preventive potentials Mahmood S. Mozaffari, Jun Yao Liu, Babak Baban A52 The status of glucocorticoid-induced leucine zipper protein in salivary gland in Sjögren’s syndrome: predictive and personalized treatment potentials Mahmood S. Mozaffari, Jun Yao Liu, Rafik Abdelsayed, Xing-Ming Shi, Babak Baban A53 Maximal aerobic capacity - important quality marker of health Jaroslav Novák, Milan Štork, Václav Zeman A54 The EMPOWER project: laboratory medicine and Horizon 2020 Wytze P. Oosterhuis, Elvar Theodorsson A55 Personality profile manifestations in patient’s attitude to oral care and adherence to doctor’s prescriptions Lyudmila Y. Orekhova, Tatyana V. Kudryavtseva, Elena R. Isaeva, Vadim V. Tachalov, Ekaterina S. Loboda A56 Results of an European survey on personalized medicine addressed to directions of laboratory medicine Mario Pazzagli, Francesca Malentacchi, Irene Mancini, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc, Ron H.N. van Schaik, Gerard Siest, Elvar Theodorsson, Chiara Di Resta A57 MCI or early dementia predictive speech based diagnosis techniques Matus Pleva, Jozef Juhar A58 Personalized speech based mobile application for eHealth Matus Pleva, Jozef Juhar A59 Circulating tumor cell-free DNA as the biomarker in the management of cancer patients Jiří Polívka jr., Filip Janků, Martin Pešta, Jan Doležal, Milena Králíčková, Jiří Polívka A60 Complex stroke care – educational programme in Stroke Centre University Hospital Plzen Jiří Polívka, Alena Lukešová, Nina Müllerová, Petr Ševčík, Vladimír Rohan A61 Sleep apnea and sleep fragmentation contribute to brain aging Kneginja Richter, Lence Miloseva, Günter Niklewski A62 Personalised approach for sleep disturbances in shift workers Kneginja Richter, Jens Acker, Guenter Niklewski A63 Medical travel and innovative PPPM clusters: new concept of integration Olga Safonicheva, Vincenzo Costigliola A64 Medical travel and women health Olga Safonicheva A65 Continuity of generations in the training of specialists in the field of reconstructive microsurgery Maxim Sautin, Janna Sinelnikova, Sergey Suchkov A66 Telemonitoring of stroke patients – empirical evidence of individual risk management results from an observational study in Germany Songül Secer, Stephan von Bandemer A67 Women’s increasing breast cancer risk with n-6 fatty acid intake explained by estrogen-fatty acid interactive effect on DNA damage: implications for gender-specific nutrition within personalized medicine Niva Shapira A68 Cytobacterioscopy of the gingival crevicular fluid as a method for preventive diagnosis of periodontal diseases Aleksandr Shcherbakov, Anatoly A. Kunin, Natalia S. Moiseeva A69 Use of specially treated composites in dentistry to avoid violations of aesthetics Bogdan R. Shumilovich, Zhanna Lipkind, Yulia Vorobieva, Dmitry A. Kunin, Anastasiia V. Sudareva A70 National eHealth system – platform for preventive, predictive and personalized diabetes care Ivica Smokovski, Tatjana Milenkovic A72 The common energy levels of Prof. Szent-Györgyi, the intrinsic chemistry of melanin, and the muscle physiopathology. Implications in the context of Preventive, Predictive, and Personalized Medicine Arturo Solís-Herrera, María del Carmen Arias-Esparza, Sergey Suchkov A73 Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja A74 Strategic aspects of higher medical education reforms to secure newer educational platforms for getting biopharma professionals matures Maria Studneva, Sihong Song, James Creeden, Мark Мandrik, Sergey Suchkov A75 Overview of the strategies and activities of the European Federation of Clinical Chemistry and Laboratory Medicine, (EFLM) Elvar Theodorsson, EFLM A76 New spectroscopic techniques for point of care label free diagnostics Syed A. M. Tofail A77 Tumor markers for personalized medicine and oncology - the role of Laboratory Medicine Ondřej Topolčan, Judita Kinkorová, Ondřej Fiala, Marie Karlíková, Šárka Svobodová, Radek Kučera, Radka Fuchsová, Vladislav Třeška, Václav Šimánek, Ladislav Pecen, Jan Šoupal, Štěpán Svačina2 A78 Modern medical terminology (MMT) as a driver of the global educational reforms Evgeniya Tretyak, Maria Studneva, Sergey Suchkov A79 Juvenile hypertension; the relevance of novel predictive, preventive and personalized assessment of its determinants Francesca M. Trovato, G. Fabio Martines, Daniela Brischetto, Daniela Catalano, Giuseppe Musumeci, Guglielmo M. Trovato A80 Proteomarkers Biotech George Th. Tsangaris, Athanasios K. Anagnostopoulos A81 Proteomics and mass spectrometry based non-invasive prenatal testing of fetal health and pregnancy complications George Th. Tsangaris, Athanasios K. Anagnostopoulos A82 Integrated Ecosystem for an Integrated Care model for Heart Failure (HF) patients including related comorbidities (ZENITH) José Verdú, German Gutiérrez, Jordi Rovira, Marta Martinez, Lutz Fleischhacker, Donna Green, Arthur Garson, Elena Tamburini, Stefano Cuomo, Juan Martinez-Leon, Teresa Abrisqueta, Hans-Peter Brunner-La Rocca, Tiny Jaarsma, Teresa Arredondo, Cecilia Vera, Giuseppe Fico, Olga Golubnitschaja, Fernando Arribas, Martina Onderco, Isabel Vara, on behalf of ZENITH consortium A83 Predictive, preventive and personalized medicine in diabetes onset and complication (MOSAIC project) José Verdú, Francesco Sambo, Barbara Di Camillo, Claudio Cobelli, Andrea Facchinetti, Giuseppe Fico, Riccardo Bellazzi, Lucia Sacchi, Arianna Dagliati, Daniele Segnani, Valentina Tibollo, Manuel Ottaviano, Rafael Gabriel, Leif Groop, Jacqueline Postma, Antonio Martinez, Liisa Hakaste, Tiinamaija Tuomi, Konstantia Zarkogianni, on behalf of MOSAIC consortium A84 Possibilities for personalized therapy of diabetes using in vitro screening of insulin and oral hypoglycemic agents Igor Volchek, Nina Pototskaya, Andrey Petrov A85 The innovative technology for personalized therapy of human diseases based on in vitro drug screening Igor Volchek, Nadezhda Pototskaya, Andrey Petrov A86 Bone destruction and temporomandibular joint: predictive markers, pathogenetic aspects and quality of life Ülle Voog-Oras, Oksana Jagur, Edvitar Leibur, Priit Niibo, Triin Jagomägi, Minh Son Nguyen, Chris Pruunsild, Dagmar Piikov, Mare Saag A87 Sub-optimal health management – global vision for concepts in medical travel Wei Wang A88 Sub-optimal health management: synergic PPPM-TCAM approach Wei Wang A89 Innovative technologies for minimal invasive diagnostics Andreas Weinhäusel, Walter Pulverer, Matthias Wielscher, Manuela Hofner, Christa Noehammer, Regina Soldo, Peter Hettegger, Istvan Gyurjan, Ronald Kulovics, Silvia Schönthaler, Gabriel Beikircher, Albert Kriegner, Stephan Pabinger, Klemens Vierlinger A90 Rare disease diobanks for personalized medicine Ayşe Yüzbaşıoğlu, Meral Özgüç, Member of EuroBioBank - European Network of DNA, Cell and Tissue Banks for Rare Disease